Life Extension Lower Back Relief contains 200 mg of a proprietary blend that combines five- leaf Chinese chaste tree extract (Vitex negundo) and ginger extract. Ginger has been studied for its effects on exercise-induced discomfort, occasional muscle soreness and support whole-body health, while Chinese chaste tree has been studied to help ease occasional discomfort relief. In a clinical trial, 79% of participants taking the Chinese chaste tree and ginger combo experienced a meaningful reduction in lower back discomfort and they started feeling results in as little as seven days.