Naturally occurring D-glucarate is found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. Life Extension's Calcium D-glucarate dietary supplement supports the body's cleansing system — a detoxification mechanism called glucuronidation. The human body uses glucuronidation to make a large variety of substances more water-soluble, and, in this way, allow for their subsequent elimination from the body.